在Spring Boot的yml文件中配置Druid数据源，可以参考以下代码：

spring:
  datasource:
    druid:
      url: jdbc:mysql://localhost:3306/your_database?useUnicode=true&characterEncoding=utf8&useSSL=false&serverTimezone=UTC
      username: your_username
      password: your_password
      driver-class-name: com.mysql.cj.jdbc.Driver
      initial-size: 5
      min-idle: 5
      max-active: 20
      max-wait: 60000
      time-between-eviction-runs-millis: 60000
      min-evictable-idle-time-millis: 300000
      validation-query: SELECT 1 FROM DUAL
      test-while-idle: true
      test-on-borrow: false
      test-on-return: false
      pool-prepared-statements: true
      max-pool-prepared-statement-per-connection-size: 20
      filters: stat,wall,log4j
      connection-properties: druid.stat.mergeSql=true;druid.stat.slowSqlMillis=5000

请将your_database、your_username和your_password替换为实际的数据库名称、用户名和密码。